Self-Assembly of Nucleocapsid-Like Particles from Recombinant Hepatitis C Virus Core Protein
نویسندگان
چکیده
منابع مشابه
Self-assembly of nucleocapsid-like particles from recombinant hepatitis C virus core protein.
Little is known about the assembly pathway and structure of hepatitis C virus (HCV) since insufficient quantities of purified virus are available for detailed biophysical and structural studies. Here, we show that bacterially expressed HCV core proteins can efficiently self-assemble in vitro into nucleocapsid-like particles. These particles have a regular, spherical morphology with a modal dist...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2001
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.75.5.2119-2129.2001